Setup wise, a useful accessory is a slotted angle plate. It gets mounted firmly to the table. Then the work gets clamped to a face. The added surface area + clamping force = increased security of drift & also rigidity. The cast iron imports can be reasonably accurate but they are heavy so beware shipping. Also the slot spacing needs to be checked vs your T-slots.
Another option is clamping stock to the table flat side down with some kind of offset riser or sacrificial board. MDF works reasonably well unless you need to a couple thou. Now you would mill 2 parallel sides say in X direction, dropping the end mill in whatever depth increments it can take. Then then take a very light finishing pass of only say 0.005". Put new clamps across & mill the 2 Y direction same way. This method gives you automatic squareness & possibly sets you up for the internal relief.
In both cases, tall + thick + steel + smaller machine is a tough combination so there are pros & cons to each. The more you can cut away with a saw the better. Also roughing end mills work well, nut just for hogging material on big boy machines. They put less stress on smaller mills. But they are not for finishing. That's why I like to have a rougher in same diamter as conventional end mill, saves on setup & calculations with just one tool change.